The indigenous communities of the Mexico-United States border region succumbed to violence, tuberculosis, venereal diseases, and the catechism. From the era of the K'miais, Cucapas, Yumas, Apaches, and Yaquis, to the present, there have been a multitude of engagements and misencounters, fusions and ruptures, innovations and oblivions. Cultures in this region continually give shape to themselves through their interactions and relations and their social organizations, contradictions, and conflicts.